Aromatic rescue of glycine in sheets

Interstrand Pairing Patterns in b-Barrel Membrane Proteins: The Positive-outside Rule, Aromatic Rescue, and Strand Registration Prediction

0022-2836/$ see front matter q 2005 E Abbreviations used: TM, transme phosphatidylethanolamine; LPS, lip E-mail address of the correspond [email protected] b-Barrel membrane proteins are found in the outer membrane of Gramnegative bacteria, mitochondria, and chloroplasts. Little is known about how residues in membrane b-barrels interact preferentially with other residues on adjacent strands. We ha...

Interstrand pairing patterns in beta-barrel membrane proteins: the positive-outside rule, aromatic rescue, and strand registration prediction.

beta-Barrel membrane proteins are found in the outer membrane of Gram-negative bacteria, mitochondria, and chloroplasts. Little is known about how residues in membrane beta-barrels interact preferentially with other residues on adjacent strands. We have developed probabilistic models to quantify propensities of residues for different spatial locations and for interstrand pairwise contact intera...

Global analysis of tandem aromatic octapeptide repeats: The significance of the aromatic-glycine motif

MOTIVATION Tandem peptide repeats play a key role in self-assembly and aggregation processes. A notable example is the occurrence of tandem peptide repeats in prionic proteins and their role in the aggregation process that leads to the formation of the prion. One of the structural characteristics that is evident from the comparison of mammalian and yeast prion proteins is the presence of aromat...

The Condensation of Aromatic Aldehydes with Glycine and Acetylglycine

The Condensation of Aromatic Aldehydes with Glycine and Acetylglycine